Kourosh Saeb-Parsy is a Lecturer at the Department of Surgery, University of Cambridge.
The focus of his multi-disciplinary research is the in vivo assessment of the function and immunogenicity of regenerative cellular therapies, including for the treatment of diabetes. His laboratory has a comprehensive programme for the generation and characterisation of human immune-reconstituted mice for use in the study of immunogenicity of stem cells and their progeny, including beta-like cells derived from induced pluripotent stem cells and endocrine pancreatic progenitors, and hepatocytes derived form induced pluripotent stem cells. He is the co-founder and coordinator of the UK Humanised Mouse Symposium (www.hms.event.cam.ac.uk) and the Director of the Cambridge Biorepository for Translational Medicine (CBTM; www.cbtm.group.cam.ac.uk ), which utilises human tissue to support major collaborations with key local and national academic institutions. CBTM will provide the infrastructure and critical access to human tissue for the generation of cellular therapies by BETA-Protect as well as for the generation of immune-reconstituted mice for the study of immunogenicity.
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